The CAR T-Cell Therapy Clinical Journey Guide

Glossary

Discharge Instructions

Instructions given to a patient when discharged from the hospital, usually by a nurse. They include important information for patients and carers to manage their own care when outside of a hospital or treatment centre. These instructions can be given in written or verbal form.

Distress

Emotional, social, spiritual or physical pain or suffering that may cause a person to feel sad, afraid, depressed, anxious or lonely. People in distress may also feel that they are not able to manage or cope with changes caused by normal life activities or by having a disease, such as cancer.

Dose escalation

A study design in which a very small dose of a treatment is given to a small number of patients. If it is found to be safe, the next group receives a higher dose. This continues until all the planned doses have been tested.